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Experts Weigh In: Does Diet Soda Increase Cancer Risk?

by Clean Plates Editors
|
May 1, 2025

If you’ve ever swapped a regular soda for a diet one to “be healthier,” you’re not alone. But while diet sodas may cut sugar, research suggests they may not be the cleanest choice for your body—especially when it comes to long-term wellness.

A recent breakdown from MD Anderson Cancer Center clarifies what we know—and don’t know—about the link between diet sodas and cancer.

So… does diet soda cause cancer?

The short answer: There’s no solid evidence (yet) that artificial sweeteners directly cause cancer in humans. But that doesn’t mean they’re harmless.

Researchers are still studying sweeteners like aspartame and sucralose, which have shown potential for negative effects in lab settings—but not enough data exists to say they definitely increase cancer risk.

In other words, the science isn’t conclusive—but caution is warranted.

Health concerns beyond cancer

Even if the cancer risk is unclear, there are other reasons to think twice about daily diet soda:

  • Cravings & weight gain: Artificial sweeteners may confuse your brain and gut, triggering more sugar cravings and appetite over time.

  • Metabolic changes: Some research suggests diet soda could interfere with blood sugar regulation and insulin sensitivity.

  • No real nutrition: Diet sodas offer zero beneficial nutrients—just sweet taste, synthetic ingredients, and empty bubbles.

Smarter swaps to try instead

The good news? You don’t have to go cold turkey. Small changes can help you reduce your intake without feeling deprived:

  • Try sparkling water with citrus or herbs

  • Sip on unsweetened iced herbal tea

  • Flavor still water with cucumber, berries, or mint

  • Keep a water bottle nearby to hydrate throughout the day

Bottom line

There’s no need to panic about the occasional diet soda. But if it’s part of your daily routine, this may be your nudge to rethink it. With no health benefits and growing questions around potential risks, it’s worth making the switch to drinks that nourish your body—not just trick your taste buds.

Want more ways to upgrade your everyday habits? Read these next:

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